Rosai-Dorfman Disease: Two Cases Report and Literature Review

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Rosai-Dorfman Disease: A Case Report and Literature Review

Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. The diagnosis is based on immunohistochemistry. Its treatment is poorly defined but the prognosis is usually favorable. Here we report a 14 year old boy who presented with massive bilateral cervi...

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Isolated intracranial Rosai-Dorfman disease: report of two cases and a review of the literature.

Rosai-Dorfman disease (RDD) is a rare but well-recognized idiopathic histioproliferative disease affecting the systemic lymph nodes. It is characterized by an unusual proliferation of histiocytic cells. Intracranial localization is a rare manifestation of RDD. The clinical and radiological differentiation from meningiomas is difficult, and can only be achieved after histological examination. Th...

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Rosai-Dorfman disease of vertebra: Case report and literature review.

Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy. Solitary extranodal skeletal lesions are extremely rare. Herein, we describe a case of isolated disease of thoracic spine, with vertebral body fracture. A 14-year-old girl presented with cervical back pain fo...

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Cutaneous rosai dorfman disease: A case report and literature review.

This study reports a clinical case of cutaneous Rosai-Dorfman disease, its manifestation, and its evolution in 10 years, thus contributing to the limited bibliography about it and which review is also an important aim of this paper. This clinical study included a histopathological and immunohistochemical review of the lesions. Since this is a skin disease, not a life-threatening condition, and ...

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rosai-dorfman disease: a case report and literature review

rosai-dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. the diagnosis is based on immunohistochemistry. its treatment is poorly defined but the prognosis is usually favorable. here we report a 14 year old boy who presented with massive bilateral cervic...

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ژورنال

عنوان ژورنال: Open Journal of Internal Medicine

سال: 2015

ISSN: 2162-5972,2162-5980

DOI: 10.4236/ojim.2015.52004